Oxidized nicotinamide adenine dinucleotide

(NAD+) is crucial to over 500 enzyme reactions in your body. NAD+ can be derived from tryptophan.

Levels of NAD+ are reduced with aging and conditions like the following:

    Diabetes
    Inflammation
    Heart disease1
 
 NAD+ is a coenzyme that is important for many pathways in the body, including the following:1

    Cellular energy
    DNA repair
    Hormone signaling
    Inflammation

It also helps maintain metabolism and circadian rhythm (the 24-hour internal clock regulating sleep cycles).2

Significantly, signaling proteins called sirtuins
require NAD+ to regulate age-related changes and extend life span